WARNING: Some of the Content here may be Objectionable to some. I have this blog labeled as "Adult Only" as a common courtesy for those who may easily be offended by Adult topics such as the Truth, Down to Earth topics, realities of living with Ovarian Cancer and/or any life threatening disease that goes along with it; Sexuality, Medicinal Cannabis, Profanity, and of course plenty of unpleasant body functions are also discussed here. This is a very tough battle for which I don't intend to hold anything back on what I am facing.

This blog is very personal and comes from the heart of a real fighting cancer patient who wishes nothing more than to live for all of those I love my own will to live, and my love of life. While sometimes I might be on heavy medication (prescribed by my doctor) and occasionally I might write about things or subjects that one may never even think about or consider; so please consider that as well. Yes; whacked out things might even be found here; but I mean everything in all good intentions.

This blog is not at all intended for the faint hearted, those who lack a sense of humor, have no idea what down to earth means, greedy mean people, and/or those who don't know how to share the world with others, and especially those who are unable to easily put themselves into the shoes of others. This blog is mostly about my journey of living my life in the best ways that I can under the Golden Rule and appreciating all of the GOOD KHARMA that comes my way! Never take anything in this world for granted; especially family and friends!

Tuesday, April 15, 2008

Another possible cure for cancer....

I just found this article which I thought was quite interesting. It's about a cheap, "safe" drug that kills most cancers. I want some of that! Well anyway here is what is really interesting taken from this article:

"The drug, dichloroacetate (DCA), has already been used for years to treat rare metabolic disorders and so is known to be relatively safe.

It also has no patent, meaning it could be manufactured for a fraction of the cost of newly developed drugs.

Evangelos Michelakis of the University of Alberta in Edmonton, Canada, and his colleagues tested DCA on human cells cultured outside the body and found that it killed lung, breast and brain cancer cells, but not healthy cells. Tumours in rats deliberately infected with human cancer also shrank drastically when they were fed DCA-laced water for several weeks.

DCA attacks a unique feature of cancer cells: the fact that they make their energy throughout the main body of the cell, rather than in distinct organelles called mitochondria. This process, called glycolysis, is inefficient and uses up vast amounts of sugar.

Until now it had been assumed that cancer cells used glycolysis because their mitochondria were irreparably damaged. However, Michelakis’s experiments prove this is not the case, because DCA reawakened the mitochondria in cancer cells. The cells then withered and died (Cancer Cell, DOI: 10.1016/j.ccr.2006.10.020).

Michelakis suggests that the switch to glycolysis as an energy source occurs when cells in the middle of an abnormal but benign lump don’t get enough oxygen for their mitochondria to work properly (see diagram). In order to survive, they switch off their mitochondria and start producing energy through glycolysis.

Crucially, though, mitochondria do another job in cells: they activate apoptosis, the process by which abnormal cells self-destruct. When cells switch mitochondria off, they become “immortal”, outliving other cells in the tumour and so becoming dominant. Once reawakened by DCA, mitochondria reactivate apoptosis and order the abnormal cells to die.

“The results are intriguing because they point to a critical role that mitochondria play:

they impart a unique trait to cancer cells that can be exploited for cancer therapy,” says Dario Altieri, director of the University of Massachusetts Cancer Center in Worcester.

The phenomenon might also explain how secondary cancers form. Glycolysis generates lactic acid, which can break down the collagen matrix holding cells together. This means abnormal cells can be released and float to other parts of the body, where they seed new tumours.

DCA can cause pain, numbness and gait disturbances in some patients, but this may be a price worth paying if it turns out to be effective against all cancers. The next step is to run clinical trials of DCA in people with cancer. These may have to be funded by charities, universities and governments: pharmaceutical companies are unlikely to pay because they can’t make money on unpatented medicines. The pay-off is that if DCA does work, it will be easy to manufacture and dirt cheap.

Paul Clarke, a cancer cell biologist at the University of Dundee in the UK, says the findings challenge the current assumption that mutations, not metabolism, spark off cancers. “The question is: which comes first?” he says.

Cancer - Learn more about one of the world’s biggest killers in our comprehensive special report."

I did write in order to find out more and will post as soon as I do. This is actually very good news and hopefully not too good to be true as suggested. What a break it will be if it does prove true. There are too many people in this world that don't deserve to die this sick and I feel I am one of them and I know of countless children as well who don't. In fact I would die for one of them if I had to. I hate seeing children sick. It breaks my heart.




Digg!

5 comments:

Petula Wright said...

This is very hopeful! I hope it turns out to be "for real."

Charming Dog Stuff said...

Please check out Oxigene.com for information on the latest clinical trials of vascular-disrupting agents (VDAs) for those suffering from cancer & eye disease:

ZYBRESTAT™ and OXi4503

You may already know about these, but in case you haven't, I hope you'll check it out. It's interesting how these drugs work- by depriving these cancer cells of their blood supply. Look into it...

And, I definitely believe in Kharma..."What comes around- CERTAINLY- goes around".

Have a great weekend,
Sheryl

ShoppingKharma said...

They do work for a little while, but most importantly they give patients a little more time. I was on Avastin for a little while as it too cuts into the blood supply to the tumor.

josh said...
This comment has been removed by the author.
josh said...

Here you can find observation data gathered by Canadian Clinic - Medicor Cancer
Centres durning DCA therapy:
http://www.medicorcancer.com/DCAtherapyData.html
and here are 4 cases treated with DCA:
http://forums.cancer.vc/respiratory-thoracic/158-case-study-1-mesothelioma-new-post.html
http://forums.cancer.vc/skin/157-case-study-2-melanoma-brain-metastases-new-post.html
http://www.medicorcancer.com/DCA-CaseStudy3.html
http://www.medicorcancer.com/DCA-CaseStudy4.html

here's an lymphoma remission story using DCA B1 vitamine protocol:
http://forums.cancer.vc/hematologic-blood/54-ds-lymphoma-story.html
and here are other remissions:

http://forums.cancer.vc/hematologic-blood/62-case-non-hodgkins-lymphoma-apparent-complete-remission.html
http://forums.cancer.vc/genitourinary-cancer/48-wim-huppes-prostate-cancer-story.html
http://forums.cancer.vc/genitourinary-cancer/55-ps-kidney-cancer-story.html
http://forums.cancer.vc/lung-cancer/56-tom-mcghees-nearly-full-remission-non-small-cell-lung-cancer.html
http://forums.cancer.vc/lung-cancer/63-lung-cancer-remission-dca.html
http://forums.cancer.vc/digestive-gastrointestinal/47-colo-rectal-cancer-story.html
http://forums.cancer.vc/digestive-gastrointestinal/57-bills-bile-duct-cancer-story.html
http://forums.cancer.vc/digestive-gastrointestinal/81-gastro-intestinal-stromal-tumors-dca.html

for more info on alternative therapies and dca see http://forums.cancer.vc and for additional info see http://puredca.com and http://cancer.vc

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Disclosure

My techniques and treatments work simply for me and may not produce the same results for others. Cancer is a very tricky disease in which it is very different in everyone it touches. No two cancers are the same just as we humans are not the same. What works for me may not work for others.

I love life and expect to live for as long as I can. I intend to use those treatments that do work for me which includes medicinal cannabis. I'm still alive with this disease over 7 years later because of this miracle plant and as long as I have my medicine available; I intend to survive many more years. I hope one day the Federal Government will eventually grow up and be led by true leaders who represent the people and not just coorporations; real people who live by the Golden Rule "treat others how you would want to be treated". I also hope the Government of the US can finally learn to admit that it has made a mortal mistake in making this life saving plant which is provided by GOD and does indeed have the ability to provide all of us with food, fuel, clothing, shelter, and medicine; a mistake that have made is that it is illegal. Yes, it was a mistake out of greed, ignorance, and racism that this miracle plant is illegal. This is a confirmed fact and we should all know and face it.

Cannabis is not at all harmful and in fact quite the opposite. Perhaps our economy can once again grow as it has in the turn of the century by making this life saving plant legal once again.

The contents of this blog including all images, (except images from third parties) and the name "Shopping Kharma - what comes around goes around" belong and copyrighted to C. Jayne Armstrong 2008-2010
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